Rosie O’Donnell has reignited her bitter feud with President Donald Trump, unleashing her most explosive accusations yet in a fiery rant about Jeffrey Epstein.

Appearing on The Jim Acosta Show, the comedian didn’t hold back: “This is a sex trafficking international coverup, he’s in the middle of it, and there’s no way—even if they redacted his name a patrillion times from the Epstein files—that he’s going to get away with it,” she said.

“Our president is a serial pedophile rapist, and that’s what he is!” O’Donnell declared.

While Trump’s name reportedly appears multiple times in the Epstein files, there’s no confirmed evidence linking him to Epstein’s crimes. The White House fired back hard, with spokesperson Abigail Jackson dismissing O’Donnell and Acosta as “two nutcases suffering from late-stage Trump Derangement Syndrome.”

O’Donnell and Trump’s feud dates back nearly two decades, but it’s hit new levels of toxicity since Trump returned to the Oval Office. After moving to Ireland in protest of his presidency, O’Donnell has regularly slammed him on social media—while Trump recently upped the ante by posting a doctored photo of her on Truth Social and suggesting he may strip her of U.S. citizenship.

O’Donnell responded with an Instagram post calling Trump “Logan Roy in gold lamé” and warning, “EPSTEIN SURVIVORS are the reckoning.”

Her latest outburst comes as pressure mounts on the Department of Justice to release more Epstein documents. Bipartisan lawmakers are pushing for full disclosure, and survivors gave emotional testimony on Capitol Hill this week, demanding transparency.

O’Donnell closed her Acosta interview with a furious vow: “For every child that was ever raped by a grown man. How dare he, Jim. How dare he!”